RME Hot Seat: Practical Approaches to Clinical Challenges in the Management of Migraine

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Support for this activity has been provided through educational grants from Allergan, Inc. and Teva Pharmaceuticals.

Release date: 5/25/2016
Expiration date: 12/17/2016
Estimated time to complete: 45 minutes


Migraine affects 12% of the US population and is classified as either episodic or chronic. Migraine is most frequently diagnosed between the ages of 30 and 40 years, and it is more common in women. Diagnosis is based on excluding other causes of headache and on assessing patient symptoms against the International Classification of Headache Disorders diagnostic criteria. Treatment includes both fast-acting acute therapies and prophylactic therapies designed to prevent the onset of migraine. Despite the availability of these therapies, the 2010 Global Burden of Disease study reported that migraine remains one of the most disabling medical conditions.

RME Hot Seat is an interactive activity designed to provide answers to some of the most common questions that clinicians have regarding the management of migraine. 

The Resource Library, which can be accessed from the main Virtual Practice map, houses tools that can aid in migraine diagnosis and management. The Resource Library also contains Day in the Life of Three Migraine Patients. This patient-focused activity identifies common causes of migraine medication nonadherence and discusses why such behaviors are detrimental to treatment efficacy. Clinicians can view Day in the Life of Three Migraine Patients for themselves and are encouraged to share it with their patients through email or in person during office visits.


Sheena K. Aurora, MD—Program Chair
Clinical Associate Professor
Department of Neurology and Neurological Sciences
Stanford University
Stanford, California

Susan L. Hutchinson, MD
Associate Clinical Professor
Department of Family Medicine
University of California-Irvine Medical Center
Director and Founder
Orange County Migraine & Headache Center
Irvine, California

B. Lee Peterlin, DO
Director, Johns Hopkins Headache Research
Associate Professor of Neurology
Johns Hopkins University School of Medicine
Baltimore, Maryland

Target Audience

This activity has been designed to meet the educational needs of neurologists, primary care physicians, and other clinicians who provide care to patients with migraine.

Learning Objectives

Upon completion of this activity, participants should be able to:

  • Identify candidates for and more effectively use prophylactic migraine therapy
  • Formulate an individualized approach for the use of acute migraine therapies that takes into consideration nonoral routes of administration when appropriate
  • Discuss the diagnosis and management of medication overuse headache

Accreditation and Credit Designation

This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of Penn State College of Medicine and RedMedEd. Penn State College of Medicine is accredited by the ACCME to provide continuing medical education for physicians.

Penn State College of Medicine designates this enduring material for a maximum of 0.75 AMA PRA Category 1 CreditTM. Physicians should claim only the credit commensurate with the extent of their participation in the activity.


Penn State College of Medicine is committed to offering CME programs that promote improvements or quality in health care and are developed free of the control of commercial interests. Reasonable efforts have been taken to ensure that our programs are balanced, independent, objective, scientific, and in compliance with regulatory requirements. Faculty, course directors, and planners have disclosed relevant financial relationships with commercial companies, and Penn State has a process in place to resolve any conflict of interest. Disclosure of a relationship is not intended to suggest or condone bias but is made to provide participants with information that might be of potential importance to their evaluation of this educational activity. Disclosures are as follows:

Sheena K. Aurora, MD, has disclosed the following relevant financial relationships:
Consultant/Advisor: Anavir, Allergan, Eneura, Nupathe
Research Grant: Allergan, Amgen, Gammacore, Teva Pharmaceuticals
Royalties/Patents: Allergan

Susan L. Hutchinson, MD, has disclosed the following relevant financial relationships:
Speakers Bureau: Allergan, Forest, Impax, Takeda, Zogenix
Consultant/Advisor: Allergan, Takeda, Zogenix

B. Lee Peterlin, DO, has disclosed the following relevant financial relationships:
Research Grant: Luitpold Pharmaceuticals, GSK Pharmaceuticals, National Institutes of Health

Planning Committee

Penn State College of Medicine staff involved in the development and review of this activity have disclosed no relevant financial relationships. 

The RedMedEd staff members involved in the development and review of this activity have disclosed no relevant financial relationships:
Thomas Finnegan, PhD, Medical Director
Denise LaTemple, PhD, Director, Scientific Services
Lauren Showers, Project Manager
Jonathan S. Simmons, ELS, Senior Managing Editor
Karen Smith, Creative Director

Unapproved Product Use

This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the US Food and Drug Administration. Penn State College of Medicine and RedMedEd do not recommend the use of any agent outside the labeled indications.


The information presented in this activity is for continuing medical education purposes only and is not meant to substitute for the independent medical judgment of a physician regarding diagnosis and treatment of a specific patient’s medical condition.

The opinions expressed in this educational activity are those of the faculty and do not necessarily represent the views of Penn State College of Medicine, RedMedEd, Allergan, Inc., or Teva Pharmaceuticals. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.

Method of Participation

There are no fees to participate in the activity. To receive CME credit, participants must review all activity information (including the learning objectives, disclosure statements, and content) and complete the posttest and program evaluation. Certificates can be printed immediately. 

For questions regarding CME credit, contact Penn State Continuing Education at (717) 531-6483 or ContinuingEd@hmc.psu.edu. Please reference activity code G5642-15-T.

Hardware/Software Requirements

  • Apple iPad or iPad mini (iOS 7 or higher) with an Internet connection
  • A computer with an Internet connection
    • Internet browser: Google Chrome, Internet Explorer 9 or higher, Firefox 26 or higher, or Safari 5 or higher
    • Additional software: Adobe Flash Player and/or an HTML 5-capable browser is required for video or audio playback; Adobe Acrobat Reader may occasionally be required


This website is managed by RedMedEd, and its printed privacy policy applies to this site. CME credit for this activity is provided by Penn State College of Medicine. If you register for CME credit for this educational activity, RedMedEd will forward relevant personally identifiable information to Penn State College of Medicine so that we can maintain records concerning credits we issue to you. We may share aggregated data concerning registrations, posttests, and evaluations. We will not knowingly share any personally identifiable information. Penn State College of Medicine may use the information you provide on this site to contact you about your CME credit or other relevant educational activities provided through Penn State College of Medicine. For more information, contact ContinuingEd@hmc.psu.edu.